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Dynamic micelles with detachable PEGylation at tumoral extracellular pH for enhanced chemotherapy

Although surface PEGylation of nanomedicines can decrease serum protein adsorption in vivo, it also blocks uptake by tumor cells. This dilemma could be overcome by employing detachably PEGylated strategy at tumoral extracellular microenvironment to achieve improved cellular uptake while prolonged ci...

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Detalles Bibliográficos
Autores principales: Yan, Guoqing, Zhang, Panpan, Wang, Jun, Wang, Xin, Tang, Rupei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750827/
https://www.ncbi.nlm.nih.gov/pubmed/33363628
http://dx.doi.org/10.1016/j.ajps.2019.11.005