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Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel

Oral therapy of tramadol, an opiate analgesic, undergoes extensive hepatic metabolism and requires frequent administration. Transdermal therapy by virtue can overcome these issues and can improve the efficacy and reduce abuse liability of tramadol. The aim of this research was to investigate the pos...

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Detalles Bibliográficos
Autores principales: Shah, Jigar, Nair, Anroop B., Shah, Hiral, Jacob, Shery, Shehata, Tamer M., Morsy, Mohamed Aly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750831/
https://www.ncbi.nlm.nih.gov/pubmed/33363633
http://dx.doi.org/10.1016/j.ajps.2019.05.001