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Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel
Oral therapy of tramadol, an opiate analgesic, undergoes extensive hepatic metabolism and requires frequent administration. Transdermal therapy by virtue can overcome these issues and can improve the efficacy and reduce abuse liability of tramadol. The aim of this research was to investigate the pos...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750831/ https://www.ncbi.nlm.nih.gov/pubmed/33363633 http://dx.doi.org/10.1016/j.ajps.2019.05.001 |