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LuxUS: DNA methylation analysis using generalized linear mixed model with spatial correlation

MOTIVATION: DNA methylation is an important epigenetic modification, which has multiple functions. DNA methylation and its connections to diseases have been extensively studied in recent years. It is known that DNA methylation levels of neighboring cytosines are correlated and that differential DNA...

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Detalles Bibliográficos
Autores principales: Halla-aho, Viivi, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750928/
https://www.ncbi.nlm.nih.gov/pubmed/32484876
http://dx.doi.org/10.1093/bioinformatics/btaa539