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Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study

BACKGROUND: Gastro-oesophageal reflux disease (GORD) is associated with multiple risk factors but determining causality is difficult. We used a genetic approach [Mendelian randomization (MR)] to identify potential causal modifiable risk factors for GORD. METHODS: We used data from 451 097 European p...

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Detalles Bibliográficos
Autores principales: Green, Harry D, Beaumont, Robin N, Wood, Andrew R, Hamilton, Benjamin, Jones, Samuel E, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, Yaghootkar, Hanieh, Weedon, Michael N, Frayling, Timothy M, Tyrrell, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750946/
https://www.ncbi.nlm.nih.gov/pubmed/32588049
http://dx.doi.org/10.1093/ije/dyaa082