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Solubility-Weighted Index: fast and accurate prediction of protein solubility
MOTIVATION: Recombinant protein production is a widely used technique in the biotechnology and biomedical industries, yet only a quarter of target proteins are soluble and can therefore be purified. RESULTS: We have discovered that global structural flexibility, which can be modeled by normalized B-...
Autores principales: | Bhandari, Bikash K, Gardner, Paul P, Lim, Chun Shen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750957/ https://www.ncbi.nlm.nih.gov/pubmed/32559287 http://dx.doi.org/10.1093/bioinformatics/btaa578 |
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