BnpC: Bayesian non-parametric clustering of single-cell mutation profiles

MOTIVATION: The high resolution of single-cell DNA sequencing (scDNA-seq) offers great potential to resolve intratumor heterogeneity (ITH) by distinguishing clonal populations based on their mutation profiles. However, the increasing size of scDNA-seq datasets and technical limitations, such as high...

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Detalles Bibliográficos
Autores principales: Borgsmüller, Nico, Bonet, Jose, Marass, Francesco, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750970/
https://www.ncbi.nlm.nih.gov/pubmed/32592465
http://dx.doi.org/10.1093/bioinformatics/btaa599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750970/
https://www.ncbi.nlm.nih.gov/pubmed/32592465
http://dx.doi.org/10.1093/bioinformatics/btaa599

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