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BnpC: Bayesian non-parametric clustering of single-cell mutation profiles
MOTIVATION: The high resolution of single-cell DNA sequencing (scDNA-seq) offers great potential to resolve intratumor heterogeneity (ITH) by distinguishing clonal populations based on their mutation profiles. However, the increasing size of scDNA-seq datasets and technical limitations, such as high...
Autores principales: | Borgsmüller, Nico, Bonet, Jose, Marass, Francesco, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria, Beerenwinkel, Niko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750970/ https://www.ncbi.nlm.nih.gov/pubmed/32592465 http://dx.doi.org/10.1093/bioinformatics/btaa599 |
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