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Existence and possible roles of independent non-CpG methylation in the mammalian brain

Methylated non-CpGs (mCpHs) in mammalian cells yield weak enrichment signals and colocalize with methylated CpGs (mCpGs), thus have been considered byproducts of hyperactive methyltransferases. However, mCpHs are cell type-specific and associated with epigenetic regulation, although their dependency...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Hun, Saito, Yutaka, Park, Sung-Joon, Nakai, Kenta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750974/
https://www.ncbi.nlm.nih.gov/pubmed/32970817
http://dx.doi.org/10.1093/dnares/dsaa020