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Factorial Mendelian randomization: using genetic variants to assess interactions

BACKGROUND: Factorial Mendelian randomization is the use of genetic variants to answer questions about interactions. Although the approach has been used in applied investigations, little methodological advice is available on how to design or perform a factorial Mendelian randomization analysis. Prev...

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Detalles Bibliográficos
Autores principales: Rees, Jessica M B, Foley, Christopher N, Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750987/
https://www.ncbi.nlm.nih.gov/pubmed/31369124
http://dx.doi.org/10.1093/ije/dyz161