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Pyrotinib Sensitizes 5-Fluorouracil-Resistant HER2(+) Breast Cancer Cells to 5-Fluorouracil

5-Fluorouracil (5-FU) is a widely used chemotherapeutic agent for breast cancer. However, acquired chemoresistance leads to a loss of its efficacy; methods to reverse are urgently needed. Some studies have shown that pyrotinib, an ErbB receptor tyrosine kinase inhibitor, is effective against HER2(+)...

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Detalles Bibliográficos
Autores principales: Yi, Jianing, Chen, Shuai, Yi, Pingyong, Luo, Jinlin, Fang, Meng, Du, Yang, Zou, Lianhong, Fan, Peizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751227/
https://www.ncbi.nlm.nih.gov/pubmed/32727638
http://dx.doi.org/10.3727/096504020X15960154585410