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Genome-wide prioritization reveals novel gene signatures associated with cardiotoxic effects of tyrosine kinase inhibitors

Tyrosine kinase inhibitors (TKIs) are characterized as multi-targeted anticancer agents that lack specificity, leading to cardiovascular adverse effects. To date, there are no reliable means to predict the cardiotoxicity of TKIs under development. The present study assessed the usual variants of gen...

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Detalles Bibliográficos
Autores principales: Li, Yilan, Wang, Weijie, Gao, Rong, Xu, Xueming, Zhang, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751338/
https://www.ncbi.nlm.nih.gov/pubmed/33376527
http://dx.doi.org/10.3892/ol.2020.12355