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Inhibition of autophagy enhances apoptosis induced by bortezomib in AML cells

Bortezomib is a novel proteasome inhibitor, which has been successfully used to treat mantle cell lymphoma and multiple myeloma. However, the direct effects of bortezomib on acute promyelocytic leukaemia (APL) have not been fully investigated. In the present study, the WST-8 assay, western blotting,...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Zhao, Yi-Ming, Yang, Ming-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751351/
https://www.ncbi.nlm.nih.gov/pubmed/33376542
http://dx.doi.org/10.3892/ol.2020.12370