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Perphenazine exerts antitumor effects on HUT78 cells through Akt dephosphorylation by protein phosphatase 2A

Sezary syndrome is a rare type of non-Hodgkin lymphoma. Protein phosphatase 2A (PP2A) is an important tumor suppressor whose activity is widely inhibited in a variety of tumors. Recently, reactivation of PP2A has attracted increasing attention as a promising approach for cancer therapy. Phenothiazin...

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Detalles Bibliográficos
Autores principales: Tsuji, Shunya, Kohyanagi, Naoki, Mizuno, Takuya, Ohama, Takashi, Sato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751355/
https://www.ncbi.nlm.nih.gov/pubmed/33376545
http://dx.doi.org/10.3892/ol.2020.12374