Hepatic stellate cell reprogramming via exosome-mediated CRISPR/dCas9-VP64 delivery

Hepatic stellate cells (HSCs) play a crucial role in the progression of liver fibrosis, which can be considered as the specific therapeutic target of anti-fibrotic treatment. Targeted induction of HSCs to hepatocytes via delivery of clustered regularly interspaced short palindromic repeats (CRISPR)/...

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Detalles Bibliográficos
Autores principales: Luo, Nianan, Li, Jiangbin, Chen, Yafeng, Xu, Yan, Wei, Yu, Lu, Jianguo, Dong, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751418/
https://www.ncbi.nlm.nih.gov/pubmed/33336604
http://dx.doi.org/10.1080/10717544.2020.1850917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751418/
https://www.ncbi.nlm.nih.gov/pubmed/33336604
http://dx.doi.org/10.1080/10717544.2020.1850917

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