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Hepatic stellate cell reprogramming via exosome-mediated CRISPR/dCas9-VP64 delivery
Hepatic stellate cells (HSCs) play a crucial role in the progression of liver fibrosis, which can be considered as the specific therapeutic target of anti-fibrotic treatment. Targeted induction of HSCs to hepatocytes via delivery of clustered regularly interspaced short palindromic repeats (CRISPR)/...
Autores principales: | Luo, Nianan, Li, Jiangbin, Chen, Yafeng, Xu, Yan, Wei, Yu, Lu, Jianguo, Dong, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751418/ https://www.ncbi.nlm.nih.gov/pubmed/33336604 http://dx.doi.org/10.1080/10717544.2020.1850917 |
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