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CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer

Cell division cycle 25 (CDC25) dual specificity phosphatases positively regulate the cell cycle by activating cyclin-dependent kinase/cyclin complexes. Here, we demonstrate that in addition to its role in cell cycle regulation, CDC25B functions as a regulator of protein phosphatase 2A (PP2A), a majo...

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Detalles Bibliográficos
Autores principales: Cairns, Junmei, Ly, Reynold C, Niu, Nifang, Kalari, Krishna R, Carlson, Erin E, Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751685/
https://www.ncbi.nlm.nih.gov/pubmed/33385163
http://dx.doi.org/10.1093/narcan/zcaa039