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4-Octyl Itaconate Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting Oxidative Stress and Inflammation

BACKGROUND: Acute lung injury (ALI) is a fatal disease in the absence of pharmacological treatment. Oxidative stress and inflammation are closely related to ALI. Innate immune cells are the main source of reactive oxygen species (ROS). Macrophages play an extremely important role in ALI through the...

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Detalles Bibliográficos
Autores principales: Li, Yang, Chen, Xing, Zhang, Hua, Xiao, Jie, Yang, Chuanlei, Chen, Weiqiang, Wei, Zhanjie, Chen, Xinzhong, Liu, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751705/
https://www.ncbi.nlm.nih.gov/pubmed/33364751
http://dx.doi.org/10.2147/DDDT.S280922