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Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors

Cancer is among the leading causes of death worldwide. One of the most challenging obstacles in cancer treatment is multidrug resistance (MDR). Overexpression of P-glycoprotein (P-gp) is associated with MDR. The growing incidence of cancer and the development of MDR drive the search for novel and mo...

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Detalles Bibliográficos
Autores principales: Garcia, Catarina, Isca, Vera M. S., Pereira, Filipe, Monteiro, Carlos M., Ntungwe, Epole, Sousa, Francisco, Dinic, Jelena, Holmstedt, Suvi, Roberto, Amílcar, Díaz-Lanza, Ana, Reis, Catarina P., Pesic, Milica, Candeias, Nuno R., Ferreira, Ricardo J., Duarte, Noélia, Afonso, Carlos A. M., Rijo, Patrícia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751738/
https://www.ncbi.nlm.nih.gov/pubmed/33364937
http://dx.doi.org/10.3389/fphar.2020.557789