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Micellized Protein Transduction Domain-Bone Morphogenetic Protein-7 Efficiently Blocks Renal Fibrosis Via Inhibition of Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition

Tubulointerstitial renal fibrosis is a chronic disease process affecting chronic kidney disease (CKD). While the etiological role of transforming growth factor-beta (TGF-β) is well known for epithelial–mesenchymal transition (EMT) in chronic kidney disease, effective therapeutics for renal fibrosis...

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Detalles Bibliográficos
Autores principales: Kim, Seonghun, Jeong, Cheol-Hee, Song, Sang Hyun, Um, Jo Eun, Kim, Hyun Sil, Yun, Jun Seop, Han, Dawool, Cho, Eunae Sandra, Nam, Bo Young, Yook, Jong In, Ku, Minhee, Yang, Jaemoon, Kim, Man-Deuk, Kim, Nam Hee, Yoo, Tae-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751754/
https://www.ncbi.nlm.nih.gov/pubmed/33364962
http://dx.doi.org/10.3389/fphar.2020.591275