Synthesis, cytotoxic assessment, and molecular docking studies of 2,6-diaryl-substituted pyridine and 3,4- dihydropyrimidine-2(1H)-one scaffolds

Cancer is one of the main global health problems. In order to develop novel antitumor agents, we synthesized 3,4-dihydropyrimidine-2(1H)-one (DHPM) and 2,6-diaryl-substituted pyridine derivatives as potential antitumor structures and evaluated their cytotoxic effects against several cancer cell line...

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Detalles Bibliográficos
Autores principales: HOSSEINZADEH, Zahra, RAZZAGHI-ASL, Nima, RAMAZANI, Ali, AGHAHOSSEINI, Hamideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751820/
https://www.ncbi.nlm.nih.gov/pubmed/33488152
http://dx.doi.org/10.3906/kim-1903-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751820/
https://www.ncbi.nlm.nih.gov/pubmed/33488152
http://dx.doi.org/10.3906/kim-1903-72

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