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Synthesis, cytotoxic assessment, and molecular docking studies of 2,6-diaryl-substituted pyridine and 3,4- dihydropyrimidine-2(1H)-one scaffolds
Cancer is one of the main global health problems. In order to develop novel antitumor agents, we synthesized 3,4-dihydropyrimidine-2(1H)-one (DHPM) and 2,6-diaryl-substituted pyridine derivatives as potential antitumor structures and evaluated their cytotoxic effects against several cancer cell line...
Autores principales: | HOSSEINZADEH, Zahra, RAZZAGHI-ASL, Nima, RAMAZANI, Ali, AGHAHOSSEINI, Hamideh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751820/ https://www.ncbi.nlm.nih.gov/pubmed/33488152 http://dx.doi.org/10.3906/kim-1903-72 |
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