UBE2N Regulates Paclitaxel Sensitivity of Ovarian Cancer via Fos/P53 Axis

BACKGROUND: Chemo-resistance is still considered one of the key factors in the mortality of ovarian cancer. In this work, we found that ubiquitin-conjugating enzyme E2 N (UBE2N) is downregulated in paclitaxel-resistant ovarian cancer cells. It suggests UBE2N to be critical in the regulation of pacli...

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Detalles Bibliográficos
Autores principales: Zhu, Qiuyuan, Chen, Jieyuan, Pan, Peipei, Lin, Feng, Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751838/
https://www.ncbi.nlm.nih.gov/pubmed/33363381
http://dx.doi.org/10.2147/OTT.S271164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751838/
https://www.ncbi.nlm.nih.gov/pubmed/33363381
http://dx.doi.org/10.2147/OTT.S271164

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