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UBE2N Regulates Paclitaxel Sensitivity of Ovarian Cancer via Fos/P53 Axis
BACKGROUND: Chemo-resistance is still considered one of the key factors in the mortality of ovarian cancer. In this work, we found that ubiquitin-conjugating enzyme E2 N (UBE2N) is downregulated in paclitaxel-resistant ovarian cancer cells. It suggests UBE2N to be critical in the regulation of pacli...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751838/ https://www.ncbi.nlm.nih.gov/pubmed/33363381 http://dx.doi.org/10.2147/OTT.S271164 |