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Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice

Changes in intracellular calcium levels in the sinus node modulate cardiac pacemaking (the calcium clock). Trimeric intracellular cation (TRIC) channels are counterion channels on the surface of the sarcoplasmic reticulum and compensate for calcium release from ryanodine receptors, which play a majo...

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Detalles Bibliográficos
Autores principales: Murakami, Manabu, Toyama, Yuichi, Yonekura, Manabu, Ohba, Takayoshi, Matsuzaki, Yasushi, Sawamura, Daisuke, Murakami, Agnieszka M., Nishi, Miyuki, Itagaki, Shirou, Tomita, Hirofumi, Takeshima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751866/
https://www.ncbi.nlm.nih.gov/pubmed/33347504
http://dx.doi.org/10.1371/journal.pone.0244254