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Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice
Changes in intracellular calcium levels in the sinus node modulate cardiac pacemaking (the calcium clock). Trimeric intracellular cation (TRIC) channels are counterion channels on the surface of the sarcoplasmic reticulum and compensate for calcium release from ryanodine receptors, which play a majo...
Autores principales: | Murakami, Manabu, Toyama, Yuichi, Yonekura, Manabu, Ohba, Takayoshi, Matsuzaki, Yasushi, Sawamura, Daisuke, Murakami, Agnieszka M., Nishi, Miyuki, Itagaki, Shirou, Tomita, Hirofumi, Takeshima, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751866/ https://www.ncbi.nlm.nih.gov/pubmed/33347504 http://dx.doi.org/10.1371/journal.pone.0244254 |
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