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In silico ADME predictions and in vitro antibacterial evaluation of 2-hydroxy benzothiazole-based 1,3,4-oxadiazole derivatives

In the present work, a library of fifteen 2-hydroxy benzothiazole-linked 1,3,4 -oxadiazole derivatives have been synthesized and confirmed using different analytical techniques. All of the synthesized compounds have been tested for antibacterial and in silico pharmacokinetic studies for the first ti...

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Detalles Bibliográficos
Autores principales: ALGHAMDI, Afnan Ahmed, ALAM, Mohammad Mahboob, NAZREEN, Syed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751938/
https://www.ncbi.nlm.nih.gov/pubmed/33488213
http://dx.doi.org/10.3906/kim-1912-55