Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases

TRIM proteins form a protein family that is characterized by a conserved tripartite motif domain comprising a RING domain, one or two B-box domains and a coiled-coil region. Members of this large protein family are important regulators of numerous cellular functions including innate immune responses...

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Detalles Bibliográficos
Autores principales: Fiorentini, Filippo, Esposito, Diego, Rittinger, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752041/
https://www.ncbi.nlm.nih.gov/pubmed/33170204
http://dx.doi.org/10.1042/BST20200383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752041/
https://www.ncbi.nlm.nih.gov/pubmed/33170204
http://dx.doi.org/10.1042/BST20200383

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