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Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis

The principle of monoclonality with regard to bacterial infections was considered immutable prior to 30 years ago. This view, espoused by Koch for acute infections, has proven inadequate regarding chronic infections as persistence requires multiple forms of heterogeneity among the bacterial populati...

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Detalles Bibliográficos
Autores principales: Hammond, Jocelyn A., Gordon, Emma A., Socarras, Kayla M., Chang Mell, Joshua, Ehrlich, Garth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752077/
https://www.ncbi.nlm.nih.gov/pubmed/33245329
http://dx.doi.org/10.1042/BST20190713