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TNF-α signaling: TACE inhibition to put out the burning heart
More than 20 years ago, Seta and colleagues hypothesized that cytokines, which are activated by myocardial injury, significantly drive heart failure progression and would therefore be effective targets to treat cardiac dysfunction. Unfortunately, several clinical trials inhibiting key cytokines like...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752092/ https://www.ncbi.nlm.nih.gov/pubmed/33296366 http://dx.doi.org/10.1371/journal.pbio.3001037 |