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Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors

Although major advances have been achieved in the treatment of chronic myeloid leukemia (CML) by using tyrosine kinase inhibitors, patients relapse after withdrawal and need long-term medication. This reflects the CML clones have not been eliminated completely. The precise mechanisms for the mainten...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyan, Yang, Yazhi, Yang, Yang, Chen, Huijun, Tu, Huaijun, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752271/
https://www.ncbi.nlm.nih.gov/pubmed/33414831
http://dx.doi.org/10.1155/2020/8890201