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(11)C-UCB-J synaptic PET and multimodal imaging in dementia with Lewy bodies

OBJECTIVE: Dementia with Lewy bodies (DLB) is a common cause of dementia, but atrophy is mild compared to Alzheimer’s disease. We propose that DLB is associated instead with severe synaptic loss, and we test this hypothesis in vivo using positron emission tomography (PET) imaging of (11)C-UCB-J, a l...

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Detalles Bibliográficos
Autores principales: Nicastro, Nicolas, Holland, Negin, Savulich, George, Carter, Stephen F., Mak, Elijah, Hong, Young T., Milicevic Sephton, Selena, Fryer, Tim D., Aigbirhio, Franklin I., Rowe, James B., O’Brien, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752786/
https://www.ncbi.nlm.nih.gov/pubmed/33381679
http://dx.doi.org/10.1186/s41824-020-00093-9