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(11)C-UCB-J synaptic PET and multimodal imaging in dementia with Lewy bodies
OBJECTIVE: Dementia with Lewy bodies (DLB) is a common cause of dementia, but atrophy is mild compared to Alzheimer’s disease. We propose that DLB is associated instead with severe synaptic loss, and we test this hypothesis in vivo using positron emission tomography (PET) imaging of (11)C-UCB-J, a l...
Autores principales: | Nicastro, Nicolas, Holland, Negin, Savulich, George, Carter, Stephen F., Mak, Elijah, Hong, Young T., Milicevic Sephton, Selena, Fryer, Tim D., Aigbirhio, Franklin I., Rowe, James B., O’Brien, John T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752786/ https://www.ncbi.nlm.nih.gov/pubmed/33381679 http://dx.doi.org/10.1186/s41824-020-00093-9 |
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