Fyn-tau Ablation Modifies PTZ-Induced Seizures and Post-seizure Hallmarks of Early Epileptogenesis

Both Fyn and tau have been associated with neuronal hyperexcitability and neurotoxicity in many tauopathies, including Alzheimer's disease (AD). Individual genetic ablation of fyn or tau appears to be protective against aberrant excitatory neuronal activities in AD and epilepsy models. It is, h...

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Detalles Bibliográficos
Autores principales: Putra, Marson, Puttachary, Sreekanth, Liu, Guanghao, Lee, Gloria, Thippeswamy, Thimmasettappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752812/
https://www.ncbi.nlm.nih.gov/pubmed/33363455
http://dx.doi.org/10.3389/fncel.2020.592374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752812/
https://www.ncbi.nlm.nih.gov/pubmed/33363455
http://dx.doi.org/10.3389/fncel.2020.592374

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