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Corticosterone Enhances the AMPK-Mediated Immunosuppressive Phenotype of Testicular Macrophages During Uropathogenic Escherichia coli Induced Orchitis

Testicular macrophages (TM) play a central role in maintaining testicular immune privilege and protecting spermatogenesis. Recent studies showed that their immunosuppressive properties are maintained by corticosterone in the testicular interstitial fluid, but the underlying molecular mechanisms are...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengguo, Jiang, Ziming, Zhang, Yiming, Zhang, Yu, Yan, Yan, Bhushan, Sudhanshu, Meinhardt, Andreas, Qin, Zhihai, Wang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752858/
https://www.ncbi.nlm.nih.gov/pubmed/33363533
http://dx.doi.org/10.3389/fimmu.2020.583276