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Corticosterone Enhances the AMPK-Mediated Immunosuppressive Phenotype of Testicular Macrophages During Uropathogenic Escherichia coli Induced Orchitis
Testicular macrophages (TM) play a central role in maintaining testicular immune privilege and protecting spermatogenesis. Recent studies showed that their immunosuppressive properties are maintained by corticosterone in the testicular interstitial fluid, but the underlying molecular mechanisms are...
Autores principales: | Zhang, Zhengguo, Jiang, Ziming, Zhang, Yiming, Zhang, Yu, Yan, Yan, Bhushan, Sudhanshu, Meinhardt, Andreas, Qin, Zhihai, Wang, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752858/ https://www.ncbi.nlm.nih.gov/pubmed/33363533 http://dx.doi.org/10.3389/fimmu.2020.583276 |
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