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Exercise Training and Neurodegeneration in Mitochondrial Disorders: Insights From the Harlequin Mouse

AIM: Cerebellar neurodegeneration is a main phenotypic manifestation of mitochondrial disorders caused by apoptosis-inducing factor (AIF) deficiency. We assessed the effects of an exercise training intervention at the cerebellum and brain level in a mouse model (Harlequin, Hq) of AIF deficiency. MET...

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Detalles Bibliográficos
Autores principales: Fernández-de la Torre, Miguel, Fiuza-Luces, Carmen, Valenzuela, Pedro L., Laine-Menéndez, Sara, Arenas, Joaquín, Martín, Miguel A., Turnbull, Doug M., Lucia, Alejandro, Morán, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752860/
https://www.ncbi.nlm.nih.gov/pubmed/33363476
http://dx.doi.org/10.3389/fphys.2020.594223