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Exercise Training and Neurodegeneration in Mitochondrial Disorders: Insights From the Harlequin Mouse
AIM: Cerebellar neurodegeneration is a main phenotypic manifestation of mitochondrial disorders caused by apoptosis-inducing factor (AIF) deficiency. We assessed the effects of an exercise training intervention at the cerebellum and brain level in a mouse model (Harlequin, Hq) of AIF deficiency. MET...
Autores principales: | Fernández-de la Torre, Miguel, Fiuza-Luces, Carmen, Valenzuela, Pedro L., Laine-Menéndez, Sara, Arenas, Joaquín, Martín, Miguel A., Turnbull, Doug M., Lucia, Alejandro, Morán, María |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752860/ https://www.ncbi.nlm.nih.gov/pubmed/33363476 http://dx.doi.org/10.3389/fphys.2020.594223 |
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