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A multi-dimensional, time-lapse, high content screening platform applied to schistosomiasis drug discovery

Approximately 10% of the world’s population is at risk of schistosomiasis, a disease of poverty caused by the Schistosoma parasite. To facilitate drug discovery for this complex flatworm, we developed an automated high-content screen to quantify the multidimensional responses of Schistosoma mansoni...

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Detalles Bibliográficos
Autores principales: Chen, Steven, Suzuki, Brian M., Dohrmann, Jakob, Singh, Rahul, Arkin, Michelle R., Caffrey, Conor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752906/
https://www.ncbi.nlm.nih.gov/pubmed/33349640
http://dx.doi.org/10.1038/s42003-020-01402-5