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Targeting the Histone Methyltransferase Disruptor of Telomeric Silencing 1-Like Restricts Avian Leukosis Virus Subgroup J Replication by Restoring the Innate Immune Response in Chicken Macrophages

Avian leukosis virus subgroup J (ALV-J), an oncogenic retrovirus, is known to cause immunosuppression and various types of cancer in chickens. Recent reports have shown that epigenetic changes in DNA and chromatin are widely implicated in the life cycle of diverse viruses, and reversal of these chan...

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Detalles Bibliográficos
Autores principales: Chen, Shihao, Wang, Dedong, Liu, Yinyin, Zhao, Ruihan, Wu, Ting, Hu, Xuming, Pan, Zhiming, Cui, Hengmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752946/
https://www.ncbi.nlm.nih.gov/pubmed/33363525
http://dx.doi.org/10.3389/fmicb.2020.603131