Single Cell Transcriptomics Implicate Novel Monocyte and T Cell Immune Dysregulation in Sarcoidosis

Sarcoidosis is a systemic inflammatory disease characterized by infiltration of immune cells into granulomas. Previous gene expression studies using heterogeneous cell mixtures lack insight into cell-type-specific immune dysregulation. We performed the first single-cell RNA-sequencing study of sarco...

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Detalles Bibliográficos
Autores principales: Garman, Lori, Pelikan, Richard C., Rasmussen, Astrid, Lareau, Caleb A., Savoy, Kathryn A., Deshmukh, Umesh S., Bagavant, Harini, Levin, Albert M., Daouk, Salim, Drake, Wonder P., Montgomery, Courtney G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753017/
https://www.ncbi.nlm.nih.gov/pubmed/33363531
http://dx.doi.org/10.3389/fimmu.2020.567342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753017/
https://www.ncbi.nlm.nih.gov/pubmed/33363531
http://dx.doi.org/10.3389/fimmu.2020.567342

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