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Single Cell Transcriptomics Implicate Novel Monocyte and T Cell Immune Dysregulation in Sarcoidosis

Sarcoidosis is a systemic inflammatory disease characterized by infiltration of immune cells into granulomas. Previous gene expression studies using heterogeneous cell mixtures lack insight into cell-type-specific immune dysregulation. We performed the first single-cell RNA-sequencing study of sarco...

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Detalles Bibliográficos
Autores principales:	Garman, Lori, Pelikan, Richard C., Rasmussen, Astrid, Lareau, Caleb A., Savoy, Kathryn A., Deshmukh, Umesh S., Bagavant, Harini, Levin, Albert M., Daouk, Salim, Drake, Wonder P., Montgomery, Courtney G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753017/ https://www.ncbi.nlm.nih.gov/pubmed/33363531 http://dx.doi.org/10.3389/fimmu.2020.567342

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