Tissue-Type Plasminogen Activator and Tenecteplase-Mediated Increase in Blood Brain Barrier Permeability Involves Cell Intrinsic Complement

Background: Tissue-type plasminogen activator (t-PA) has been the mainstay of therapeutic thrombolysis for patients with acute ischaemic stroke (AIS). However, t-PA can cause devastating intracerebral hemorrhage. t-PA can also influence the CNS in part by modulation of BBB permeability. Complement a...

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Detalles Bibliográficos
Autores principales: Keragala, Charithani B., Woodruff, Trent M., Liu, Zikou, Niego, Be'eri, Ho, Heidi, McQuilten, Zoe, Medcalf, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753024/
https://www.ncbi.nlm.nih.gov/pubmed/33363504
http://dx.doi.org/10.3389/fneur.2020.577272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753024/
https://www.ncbi.nlm.nih.gov/pubmed/33363504
http://dx.doi.org/10.3389/fneur.2020.577272

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