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Deoxyfluorination of acyl fluorides to trifluoromethyl compounds by FLUOLEAD(®)/Olah’s reagent under solvent-free conditions

A new protocol enabling the formation of trifluoromethyl compounds from acyl fluorides has been developed. The combination of FLUOLEAD(®) and Olah’s reagent in solvent-free conditions at 70 °C initiated the significant deoxyfluorination of the acyl fluorides and resulted in the corresponding trifluo...

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Detalles Bibliográficos
Autores principales: Liang, Yumeng, Taya, Akihito, Zhao, Zhengyu, Saito, Norimichi, Shibata, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753111/
https://www.ncbi.nlm.nih.gov/pubmed/33414852
http://dx.doi.org/10.3762/bjoc.16.254