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High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale
Protein-protein interactions (PPIs) are of fundamental importance for our understanding of physiology and pathology. PPIs involving short, linear motifs play a major role in immunological recognition, signaling, and regulation and provide attractive starting points for pharmaceutical intervention. Y...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753147/ https://www.ncbi.nlm.nih.gov/pubmed/33364586 http://dx.doi.org/10.1016/j.isci.2020.101898 |