Cargando…

Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain

OBJECTIVES: The dorsal vagal complex (DVC) senses insulin and controls glucose homeostasis, feeding behaviour and body weight. Three-days of high-fat diet (HFD) in rats are sufficient to induce insulin resistance in the DVC and impair its ability to regulate feeding behaviour. HFD-feeding is associa...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Bianca, New, Lauryn E., Griffiths, Joanne C., Deuchars, Jim, Filippi, Beatrice M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753200/
https://www.ncbi.nlm.nih.gov/pubmed/33227495
http://dx.doi.org/10.1016/j.molmet.2020.101123