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Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain
OBJECTIVES: The dorsal vagal complex (DVC) senses insulin and controls glucose homeostasis, feeding behaviour and body weight. Three-days of high-fat diet (HFD) in rats are sufficient to induce insulin resistance in the DVC and impair its ability to regulate feeding behaviour. HFD-feeding is associa...
Autores principales: | Patel, Bianca, New, Lauryn E., Griffiths, Joanne C., Deuchars, Jim, Filippi, Beatrice M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753200/ https://www.ncbi.nlm.nih.gov/pubmed/33227495 http://dx.doi.org/10.1016/j.molmet.2020.101123 |
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