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A multicomponent screen for feeding behaviour and nutritional status in Drosophila to interrogate mammalian appetite-related genes

OBJECTIVE: More than 300 genetic variants have been robustly associated with measures of human adiposity. Highly penetrant mutations causing human obesity do so largely by disrupting satiety pathways in the brain and increasing food intake. Most of the common obesity-predisposing variants are in, or...

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Detalles Bibliográficos
Autores principales: Chalmers, J., Tung, Y.C.L., Liu, C.H., O'Kane, C.J., O'Rahilly, S., Yeo, G.S.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753202/
https://www.ncbi.nlm.nih.gov/pubmed/33242659
http://dx.doi.org/10.1016/j.molmet.2020.101127