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A multicomponent screen for feeding behaviour and nutritional status in Drosophila to interrogate mammalian appetite-related genes
OBJECTIVE: More than 300 genetic variants have been robustly associated with measures of human adiposity. Highly penetrant mutations causing human obesity do so largely by disrupting satiety pathways in the brain and increasing food intake. Most of the common obesity-predisposing variants are in, or...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753202/ https://www.ncbi.nlm.nih.gov/pubmed/33242659 http://dx.doi.org/10.1016/j.molmet.2020.101127 |