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Quercitrin alleviates cartilage extracellular matrix degradation and delays ACLT rat osteoarthritis development: An in vivo and in vitro study

Introduction: Disruptions of extracellular matrix (ECM) degradation homeostasis play a significant role in the pathogenesis of osteoarthritis (OA). Matrix metalloproteinase 13 (MMP13) and collagen Ⅱ are important components of ECM. Earlier we found that quercitrin could significantly decrease MMP13...

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Detalles Bibliográficos
Autores principales: Guo, Hanli, Yin, Weifeng, Zou, Ziling, Zhang, Chao, Sun, Minghui, Min, Lingtian, Yang, Lei, Kong, Lingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753236/
https://www.ncbi.nlm.nih.gov/pubmed/33364061
http://dx.doi.org/10.1016/j.jare.2020.06.020