Cargando…

Quercitrin alleviates cartilage extracellular matrix degradation and delays ACLT rat osteoarthritis development: An in vivo and in vitro study

Introduction: Disruptions of extracellular matrix (ECM) degradation homeostasis play a significant role in the pathogenesis of osteoarthritis (OA). Matrix metalloproteinase 13 (MMP13) and collagen Ⅱ are important components of ECM. Earlier we found that quercitrin could significantly decrease MMP13...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Hanli, Yin, Weifeng, Zou, Ziling, Zhang, Chao, Sun, Minghui, Min, Lingtian, Yang, Lei, Kong, Lingyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753236/ https://www.ncbi.nlm.nih.gov/pubmed/33364061 http://dx.doi.org/10.1016/j.jare.2020.06.020

Ejemplares similares

Expression of VEGF-A Signaling Pathway in Cartilage of ACLT-induced Osteoarthritis Mouse Model
por: Qian, Jia-jia, et al.
Publicado: (2021)

Tongbi Huoluo Decoction alleviates cartilage degeneration in knee osteoarthritis by inhibiting degradation of extracellular matrix
por: Chen, Weijian, et al.
Publicado: (2023)

Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix
por: Wang, Yafei, et al.
Publicado: (2017)

Cordycepin Alleviates Anterior Cruciate Ligament Transection (ACLT)-Induced Knee Osteoarthritis Through Regulating TGF-β Activity and Autophagy
por: Tao, Xiao-Mei, et al.
Publicado: (2020)

Cordycepin Alleviates Anterior Cruciate Ligament Transection (ACLT)-Induced Knee Osteoarthritis Through Regulating TGF-β Activity and Autophagy [Retraction]
Publicado: (2020)

Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat
por: Zhu, Huangrong, et al.
Publicado: (2022)

MiR-760 targets HBEGF to control cartilage extracellular matrix degradation in osteoarthritis
por: Zhu, Yingchun, et al.
Publicado: (2023)

Oral shea nut oil triterpene concentrate supplement ameliorates pain and histological assessment of articular cartilage deterioration in an ACLT injured rat knee osteoarthritis model
por: Chen, Ing-Jung, et al.
Publicado: (2019)

Resveratrol inhibits apoptosis by increase in the proportion of chondrocytes in the S phase of cell cycle in articular cartilage of ACLT plus Mmx rats
por: Wang, Yu, et al.
Publicado: (2019)

Increased elastic modulus of the synovial membrane in a rat ACLT model of osteoarthritis revealed by atomic force microscopy
por: Dai, Shouqian, et al.
Publicado: (2020)

Combined detection of serum CTX‐II and C2C in a rat model of ACLT‐induced osteoarthritis
por: Yu, Fei, et al.
Publicado: (2023)

Natural Compounds: Potential Therapeutics for the Inhibition of Cartilage Matrix Degradation in Osteoarthritis
por: Ashruf, Omer S., et al.
Publicado: (2022)

The Role of Changes in Extracellular Matrix of Cartilage in the Presence of Inflammation on the Pathology of Osteoarthritis
por: Maldonado, Maricela, et al.
Publicado: (2013)

Knockout of miR-21-5p alleviates cartilage matrix degradation by targeting Gdf5 in temporomandibular joint osteoarthritis
por: Zhang, Aobo, et al.
Publicado: (2020)

Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo
por: Pang, Zhiying, et al.
Publicado: (2021)

Targeting Cartilage Degradation in Osteoarthritis
por: McClurg, Oliver, et al.
Publicado: (2021)

Computational insights into the substrate recognition mechanism of cartilage extracellular matrix degradation
por: Lai, Yen-Yu, et al.
Publicado: (2021)

Inhibition of fibroblast activation protein ameliorates cartilage matrix degradation and osteoarthritis progression
por: Fan, Aoyuan, et al.
Publicado: (2023)

Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix–related Genes in a Rat Model of Osteoarthritis
por: Dai, Linghui, et al.
Publicado: (2015)

Aggrecanases and cartilage matrix degradation
por: Nagase, Hideaki, et al.
Publicado: (2003)

A small molecule promotes cartilage extracellular matrix generation and inhibits osteoarthritis development
por: Shi, Yuanyuan, et al.
Publicado: (2019)

The effect of cartilage decellularized extracellular matrix-chitosan compound on treating knee osteoarthritis in rats
por: Chen, Deng, et al.
Publicado: (2021)

Decreased Sulfate Content and Zeta Potential Distinguish Glycosaminoglycans of the Extracellular Matrix of Osteoarthritis Cartilage
por: Nunes, Rodolfo de Melo, et al.
Publicado: (2021)

MiR-99a alleviates apoptosis and extracellular matrix degradation in experimentally induced spine osteoarthritis by targeting FZD8
por: Wang, Yeyang, et al.
Publicado: (2022)

Quercitrin Ameliorates Hyperlipidemia and Hepatic Steatosis in Ovariectomized Mice
por: Hur, Haeng Jeon, et al.
Publicado: (2020)

Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis
por: XU, YING, et al.
Publicado: (2014)

Cartilage destruction by matrix degradation products
por: Yasuda, Tadashi
Publicado: (2006)

Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis
por: Xu, Lingxiao, et al.
Publicado: (2016)

Alleviation of Cartilage Destruction by Sinapic Acid in Experimental Osteoarthritis
por: Cai, Dawei, et al.
Publicado: (2019)

Developmental Mechanisms in Articular Cartilage Degradation in Osteoarthritis
por: Tchetina, Elena V.
Publicado: (2011)

Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats
por: Ma, Tianwen, et al.
Publicado: (2022)

Tropoelastin-Pretreated Exosomes from Adipose-Derived Stem Cells Improve the Synthesis of Cartilage Matrix and Alleviate Osteoarthritis
por: Meng, Shuo, et al.
Publicado: (2023)

Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo
por: Zheng, Wenhao, et al.
Publicado: (2017)

miR-107 affects cartilage matrix degradation in the pathogenesis of knee osteoarthritis by regulating caspase-1
por: Qian, Jiatian, et al.
Publicado: (2021)

Quercitrin, an Inhibitor of Sortase A, Interferes with the Adhesion of Staphylococcal aureus
por: Liu, Bingrun, et al.
Publicado: (2015)

Articular cartilage and changes in arthritis: Matrix degradation
por: Mort, John S, et al.
Publicado: (2001)

Isorhynchophylline alleviates cartilage degeneration in osteoarthritis by activating autophagy of chondrocytes
por: Jiang, Jieyun, et al.
Publicado: (2023)

Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes
por: Son, Young-Ok, et al.
Publicado: (2017)

Bardoxolone methyl ameliorates osteoarthritis by inhibiting osteoclastogenesis and protecting the extracellular matrix against degradation
por: Yang, Ruijia, et al.
Publicado: (2023)

Inhibition of Shedding of Low‐Density Lipoprotein Receptor–Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis
por: Yamamoto, Kazuhiro, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3p2cs4tv37dcggd0j6b98olmdi